The following is a full listing of the cast for the episode "Letting Go".
- Chad Michael Murray as Lucas Scott
- James Lafferty as Nathan Scott
- Hilarie Burton as Peyton Sawyer
- Bethany Joy Lenz as Haley James Scott
- Sophia Bush as Brooke Davis
- Barbara Alyn Woods as Deb Lee
- Lee Norris as Marvin "Mouth" McFadden
- Antwon Tanner as Antwon "Skills" Taylor
- Jackson Brundage as Jamie Scott
- Lisa Goldstein as Millicent Huxtable
- Evan Peters as Jack Daniels
Credited Without Appearance
Community content is available under CC-BY-SA unless otherwise noted.